Genetic Diversity and New Lineages of Dengue Virus Serotypes 3 and 4 in Returning Travelers, Germany, 2006–2015
نویسندگان
چکیده
During 2006-2015, we analyzed 70 dengue virus (DENV) strains isolated from febrile travelers returning to Germany. High genetic diversity, including multiple co-circulating DENV lineages and emerging new lineages of DENV-3 and DENV-4, was demonstrated. Our passive surveillance system based on returning travelers yielded substantial information on DENV diversity.
منابع مشابه
Emergence of a New Lineage of Dengue Virus Type 2 Identified in Travelers Entering Western Australia from Indonesia, 2010-2012
Dengue virus (DENV) transmission is ubiquitous throughout the tropics. More than 70% of the current global dengue disease burden is borne by people who live in the Asia-Pacific region. We sequenced the E gene of DENV isolated from travellers entering Western Australia between 2010-2012, most of whom visited Indonesia, and identified a diverse array of DENV1-4, including multiple co-circulating ...
متن کاملDengue viruses in Papua New Guinea: evidence of endemicity and phylogenetic variation, including the evolution of new genetic lineages
Dengue is the most common cause of mosquito-borne viral disease in humans, and is endemic in more than 100 tropical and subtropical countries. Periodic outbreaks of dengue have been reported in Papua New Guinea (PNG), but there is only limited knowledge of its endemicity and disease burden. To help elucidate the status of the dengue viruses (DENVs) in PNG, we performed envelope (E) gene sequenc...
متن کاملProbable Importation of Dengue Virus Type 4 to Angola from Brazil
To the Editor: The prevalence of dengue virus (DENV) infection in Africa may have been grossly underestimated for many years (1). Even though published reports are scarce, dengue has been documented in at least 34 countries in Africa (2). The role of travelers as sentinels of infectious disease has proven to be invaluable in this regard; dengue in returning travelers was the only evidence for l...
متن کاملAir Travel Is Associated with Intracontinental Spread of Dengue Virus Serotypes 1–3 in Brazil
Dengue virus and its four serotypes (DENV-1 to DENV-4) infect 390 million people and are implicated in at least 25,000 deaths annually, with the largest disease burden in tropical and subtropical regions. We investigated the spatial dynamics of DENV-1, DENV-2 and DENV-3 in Brazil by applying a statistical framework to complete genome sequences. For all three serotypes, we estimated that the int...
متن کاملAn Imported Case of Dengue Fever in Iran, 2015
Background: Dengue fever is a mosquito-borne disease which is not known to be endemic in Iran. Case Report: In October 2015, a 32-year-old Iranian woman was admitted with acute unexplained high-grade fever, headache, pain, rash, diarrhea, leukopenia and elevated liver enzymes after returning from India. Serological and molecular analysis for Dengue virus (DENV) infection revealed positive ...
متن کامل